Abstract

Background: Contrast induced nephropathy (CIN) is one of the common cause for hospital acquired renal failure in patients undergoing coronary angioplasty for acute myocardial infarction. The aim of this study was to assess the renal function in patients after primary coronary angioplasty by estimating the levels of serum creatinine (Sr. Cr) Materials and Methods: Sample sizes of 51 subjects were included for the study. Serum creatinine levels were measured before and after the procedure. The difference in Serum creatinine levels was calculated.CIN was defined as increase in Sr Cr >0.5 or >25% compared to the baseline value. Results: Out of the 51 cases, CIN occurred in 7.8% (4 cases). In addition,19.6 %( 10 cases) had pre-existing renal insufficiency out of which 3 subjects developed CIN.According to recently proposed

Highlights

  • Contrast induced nephropathy (CIN) is a common complication in patients undergoing percutaneous coronary interventions, with a mortality rate of 30%1

  • This study shows CIN is a common complication in patients undergoing percutaneous coronary interventions

  • In the present study the incidence is more in patients with serum creatinine level >1.2mg/dL and is statistically significant (P=0.004) when compared within the groups

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Summary

Introduction

Contrast induced nephropathy (CIN) is a common complication in patients undergoing percutaneous coronary interventions, with a mortality rate of 30%1. A recent definition of contrast nephropathy in patients undergoing percutaneous coronary intervention was proposed by Harjai, et al 4 This tripartite definition classifies contrast nephropathy as grade 0 (serum creatinine increase

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