Risk factors of depression in patients with functional dyspepsia

Abstract

Objective To explore the risk factors of depression in patients with functional dyspepsia. Methods From July 2014 to September 2014, a total of 295 patients was diagnosed of functional dyspepsia (FD). All of them were evaluated with the 17-item Hamilton Depression Rating Scale (HAMD-17). They were divided into two groups: FD with depression and FD without depression. Socio-demographic and clinical features were collected and analyzed. Logistic regression analysis was used to detect risk factors of depression in FD patients. Results In our studies, 20.0% (59/295) of FD patients were diagnosed as depression. Risk factors for depression were age, disease duration, and marriage in univariate analysis, and marriage and disease duration in multivariate analysis. FD patients with moderate to severe depression had a longer duration of disease and more sessions of gastroscopy than those with mild depression. Conclusions Prevalence of depression is higher in FD patients with incomplete marriage and long disease duration, routine depression screening should be carried out for these patients. Key words: Dyspepsia/CO; Depressive disorder/CO; Risk factors