Risk factors of acute cenencephalocele during craniotomy in patients with craniocerebral injury

Abstract

Objective To analyze the risk factors of acute cenencephalocele during craniotomy in patients with craniocerebral injury. Methods The clinical data of 108 patients with craniocerebral injury treated by craniotomy in Shandong Energy Zaozhuang Mining Group Central Hospital from October 2017 to September 2018 were retrospectively analyzed. And the patients were divided into two groups according to whether acute cenencephalocele occurred during craniotomy. Fifty patients with intraoperative acute cenencephalocele were set as observation group and 58 patients without intraoperative acute cenencephalocele were set as control group. The clinical data of patients were collected and the influencing factors of acute cenencephalocele were analyzed. Results There was no statistically significant difference between the two groups in gender, age, comorbidity of multiple injuries, causes of injury or cerebrospinal fluid leakage (P>0.05). There were significant differences in the time from injury to operation, the first Glasgow coma score (GCS) after admission, comorbidity rate of contralateral skull fracture, post traumatic acute diffuse brain swelling (PADBS) and delayed traumatic intracranial hematoma (DTIH) between the two groups (P<0.05). Multivariate Logistic regression analysis showed that the time from injury to operation, the first GCS after admission, comorbidity of contralateral skull fracture, PADBS and DTIH were risk factors for acute cenencephalocele during craniotomy (P<0.05). Conclusions The time from injury to operation, the first GCS after admission, comorbidity of contralateral skull fracture, PADBS and DTIH are risk factors for acute cenencephalocele during craniotomy. Specific nursing measures should be developed to reduce the occurrence risk of acute cenencephalocele in clinical. Key words: Craniocerebral injury; Acute cenencephalocele; Craniotomy; Risk factor