Risk Factors Influencing Development Of Surgical Site Infection In Patients Who Were Operated Due To Endometrial Cancer

Abstract

Endometrial cancer is the most commonly encountered malignancy of female genital system. Surgery is the main treatment approach in endometrial cancer. The frequency of surgical site infections (SSI) has recently increased. Prediction of risk factors which may cause SSI and taking due precautions may provide a decrease in frequency of these infections. The aim of this study was to determine the risk factors for SSI after surgery for endometrial cancer. The medical records of patients who were operated due to endometrial cancer in Kanuni Sultan Suleyman Education and Research Hospital between January 1, 2015, and July 31, 2015, were retrospectively reviewed. The patients were divided into two groups; those that developed SSI following the operation and those that did not develop SSI. SSI was diagnosed based on Center for Disease Control and Prevention criteria. Ages, comorbid diseases, body mass index, American Society of Anesthesiologists (ASA) scores, smoking, durations of operation, the presence of drainage, blood transfusion, pre-operative hemoglobin level, and pre-operative glucose level of patients were recorded. A P < 0.05 was considered to be statistically significant. Of the 103 patients included, 12 patients (11.65%) developed SSI. We found a relationship between SSI development and high body mass index; the presence of diabetes mellitus, presence of transfusion, and high pre-operative glucose level. No relationship among age, hypertension, smoking, ASA score, presence of drainage, duration of operation, pre-operative hemoglobin level, and development of SSI has been determined. In conclusion, although there are patient-related and non-modifiable risk factors, we are in thought of that prediction of modifiable risk factors, such as blood glucose level, may reduce the frequency of SSI after endometrial cancer surgery.