Abstract
：Two hundred male and 200female patients with type 2 diabetes mellitus admitted from January 2007 to April 2008were enrolled in the study. Of them, 267 were diagnosed as non-alcoholic fatty liverdisease (NAFLD) by ultrasonography. The measurements included:body mass index (BMI),waist-to-hip ratio (WHR) ,fasting blood glucose( FBG), ALT, AST, total bilirubin(TBIL),cholesterol(CHO),triglyceride(TG), high density lipoprotein cholesterol (HDL-C), lowdensity lipoprotein cholesterol ( LDL-C) ,serum creatinine (Cr), supersensitive C-reactiveprotein (hsCRP) and urine albumin/creatinine. The relationship of above factors with NAFLDwas determined. Our data showed that male NAFLD patients were in general younger thanfemale. The BMI ( t = 11. 361, P = 0. 000), waist circumference ( t = 9. 771, P =0. 000),hip circumference (t = 10. 469, P =0. 000) ,TG(t =7. 352, P =0. 000) and hsCRP (t =2.242,P =0. 026) of NAFLD patients were significantly higher than those without NAFLD. ThehsCRP of patients with central obesity was also significantly higher than those withoutcentral obesity (t = 0. 266, P = 0. 045 ).BMI and TG were positively correlated withNAFLD. Waist circumference was an independent factor of NAFLD in male patients, same aship circumference with NAFLD in female patients. In conclusion, gender,central obesity anddyslipidemia may be risk factors for NAFLD in patients with type 2 diabetes mellitus.
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