Abstract
Metastatic breast cancer is the second most common cancer associated with brain metastases;it has become a major life-limiting problem in those patients with metastatic breast cancer.This study aimed to detect early brain metastasis and intent to manage so to decrease disability and mortality in patients with breast cancer.This is a retrospective study analysing patients with metastatic breast cancer during the period from February 2018 to August 2019 at Basrah Oncology Centre which is the main tertiary referral hospital serving the southern part of Iraq. During the study duration (around 18 months), we found that risk factors for developing brain metastasis are tumour size, nodal involvement, tumour grade, hormone receptor (if negative), human epidermal growth factor2 (If positive) and radiotherapy (if not given as adjuvant) .In conclusion, the tumour size, grade, nodal involvement, whether the hormone receptors positive or negative, and if the patient received radiotherapy or not, all are predictive factors tobe considered, so patients should have appropriate imaging technique.Key words: Brain metastasis, breast cancer, risk factors.
Highlights
Breast cancer is one of the most in growing health issues that threats female globally and especially in the developing countries because of the poor facilities and low socioeconomic status
The early detection of the breast cancer through screening is increasing around the world, this increment because of the improvement in early detection and screening programs as well as the rising of educational level[21]
In our study we found a decrease in the total number of the registered cases in the time between 2018 and 2020, this might explained by increase in the number of private breast clinics in the governorate within the hospitals or the primary health centers, Regarding the year 2019-2020 the attendance to the screening clinic declining might be due to the Pandemic of COVID-19 which makes people aware about the attendance to hospitals and primary health centers to avoid get infection with SARS COV 2 virus, adding to that the public curfew
Summary
Breast cancer is one of the most in growing health issues that threats female globally and especially in the developing countries because of the poor facilities and low socioeconomic status. A new research stated that about 1.7 million new cases of breast cancers reported globally each year and 60% deaths of breast cancer or its complications happened in the developing countries[3]. These countries depend on their national healthcare system in the screening process and early detection, which are poorly equipped, and need more training and experience[4]. An increased risk of breast cancer in women with a family history of breast cancer has been demonstrated by many studies using a variety of study designs This depends mainly on the type of relative relationship, if more than one relative were affected, in addition to the age of getting the cancer[7]. This study aimed to determine the general socio-demographic characteristics of breast cancer screened cases among women above 35 years in Basrah and to detect malignant cases among BIRAD 1
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