Abstract
Chronic Hepatitis C virus (HCV) infection is closely associated with cirrhosis and with the prospective risk of Hepato-Cellular-Carcinoma (HCC). The long-term duration required for HCV transforming into HCC necessitates thorough study of various co-morbidities associated with HCV patients, some of which may act as predictors of HCC. Present paper reports co-morbidities among HCV patients. This is a hospital-based study. The patients reporting to Outdoor Patient Department (OPD) of Sharda hospital, Greater Noida, UP, India were enrolled for the study. Total number of 134 HCV positive patients were studied for the parameters pertaining to Liver Function Test (LFT), Kidney Function Test (KFT), Complete Blood Count (CBC). Of the 134 patients included in the study 31.34% were smokers and alcoholics and reported to the hospital with complaints of abdominal pain. Few patients (1.49%) presented the evidence of Chronic Liver Disease and/or cirrhosis. Among 61.9% patients high SGOT levels than normal and among 38.8% patients high SGPT levels were observed. Kidney function parameters viz; high levels of chloride are 29.85% of study subjects and higher levels of uric acid was observed in 18.6% of study subjects. In 55.55% of patients low levels of Hb was observed. Our study shows a parallel trend of abnormal parameters in the LFT, KFT and CBC parameters of HCV patients. The important lead is the simultaneous dysfunction of liver and kidney impacting upon haemoglobin which may lead to seriousness of respiratory efficiency caused due to low haemoglobin.
Published Version
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