Risk Factors for Preeclampsia in Pregnant Women with Pregestational Diabetes

Abstract

Purpose: To estimate the incidence of preeclampsia in pregnant women with pregestational diabetes and to identify risk factors for preeclampsia. Material and methods: A retrospective cohort study of pregnant women with pregestational diabetes was conducted and compared with a random sample of non-diabetic pregnant women from the population served in the period from January 2017 to August 2019 at the Obstetrics Service of the Women's Hospital. By means of multiple logistic regression the risk factors for preeclampsia were estimated. Results: 10% and 90% of the cases were type 1 and type 2 diabetes mellitus respectively. The incidence of preeclampsia in pregestational diabetes mellitus was 22.5%. Chronic hypertension (OR: 28, CI95%4.8,164) for global PE, nulliparity (OR:6.8, CI95%1.6,36.2) for PE with SF, metabolic disorder (OR:8.4, CI95%1.3,54) for early-onset PE. Conclusions: Chronic hypertension, nulliparity, and metabolic disorder were risk factors for preeclampsia in pregnant women with pregestational diabetes.