Abstract

BackgroundPostoperative deep infection after bone tumor surgery remains a serious complication. Although there are numerous reports about risk factors for postoperative deep infection in general surgery, there is only a small number of reports about those for bone tumor surgery. This retrospective study aimed to identify risk factors for postoperative deep infection after bone tumor resection.MethodsWe reviewed data of 681 patients (844 bone tumors) who underwent surgery. Associations between variables, including age, recurrent tumor, pathological fracture, surgical site (pelvis/other), chemotherapy, biological reconstruction, augmentation of artificial bone or bone cement, the use of an implant, intraoperative blood loss, operative time, additional surgery for complications, and postoperative deep infection were evaluated.ResultsThe rate of postoperative deep infection was 3.2% (27/844 tumors). A pelvic tumor (odds ratio [OR]: 3.4, 95% confidence interval [CI]: 1.0–11.3) and use of an implant (OR: 9.3, 95% CI: 1.9–45.5) were associated with an increased risk of deep infection.ConclusionsThis retrospective study showed that pelvic tumor and use of an implant were independent risk factors for deep infection. This information will help surgeons prepare an adequate surgical plan for patients with bone tumors.

Highlights

  • Deep infection is one of the most serious complications after surgery

  • To improve the outcome of bone tumor surgery, the risk of each surgery should be assessed and patients with high risk of deep infection should be treated with preventive measures such as nutritional optimization, perioperative antibiotics or MRSA nasal screening and decolonization

  • There are numerous reports describing risk factors for postoperative deep infection after orthopedic surgery, including arthroplasty and spine surgery, only a small number of studies have reported those after bone tumor surgery [5,7,8,9,10,11]

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Summary

Background

Postoperative deep infection after bone tumor surgery remains a serious complication. There are numerous reports about risk factors for postoperative deep infection in general surgery, there is only a small number of reports about those for bone tumor surgery. This retrospective study aimed to identify risk factors for postoperative deep infection after bone tumor resection

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