Abstract
Background & Objectives: The Coronavirus disease 2019 (COVID -19 ) pandemic has posed a devastating global impact, with millions of cases which vary widely in the disease severity. Southeastern Iran has been particularly hard hit, with a high number of patients requiring hospitalization. This study aimed to identify risk factors associated with mortality from COVID -19 among hospitalized patients in this region. Materials & Methods: A case -control study compared hospitalized COVID -19 patients who succumbed to the disease (confirmed by death certificates and positive polymerase chain reaction or PCR tests) with those who recovered, from February 27, 2020, to June 30, 2021. Researchers analyzed data using t -tests and chi - square tests to identify significant factors associated with mortality (p < 0.05). Variables significant at a less stringent level (p < 0.2) were then included in a backward logistic regression model to explore independent predictors of mortality. Results: This retrospective study examined data from 473 patients, of whom 158 were in the case group and 315 were in the control group. Among the case group, 80.4% were elderly, compared to 41% in the control group. A significantly higher proportion of patients in the case group (12.7%) experienced critical symptoms leading to the ICU hospitalization, compared to the control group (7.3%). Multivariable regression analysis identified several factors significantly associated with increased mortality risk. These included ICU hospitalization (OR=5.27, CI: 3.09 -8.98), advanced age (OR=4.06, CI: 2.43 -6.80), hypertension (OR=4.44, CI: 1.52 -12.93), cardiovascular diseases (OR=2.56, CI: 1.1 -5.98), and critical symptoms (OR=2.74, CI: 1.92 - 8.04). Diabetes, pregnancy, nationality, and gender did not statistically increase mortality risk (p -value ≥ 0.05). Conclusion : Advanced age, severe symptoms requiring ICU care, hypertension, and cardiovascular diseases are all critical mortality risk factors in hospitalized COVID -19 patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
