Abstract
Mycobacterium bovis is a bacterium belonging to the Mycobacterium tuberculosis complex that causes tuberculosis in cattle and in other domestic and wild animals, as well as in humans. Disease control measures are carried out by slaughtering animals tested positive in the intradermal tuberculinization test and sanitation of their original living spaces, in addition to epidemiological surveillance carried out through the sanitary inspection of bovine carcasses in slaughterhouses. In the latter, official inspection services collect samples from macroscopic lesions suspected of bovine tuberculosis, which are then sent for laboratory analysis. Knowledge concerning the variables associated with the occurrence of M. bovis can aid in decision-making regarding control and disease eradication efforts. In this context, the aim of this study was to identify the risk factors for a positive M. bovis diagnosis in suspected bovine tuberculosis lesions obtained during epidemiological surveillance activities in the state of Mato Grosso, Brazil. A total of 105 suspicious lesions were analyzed using the Nested Polymerase Chain Reaction (nested q-PCR) method, of which 14 (13.33%) tested positive for M. bovis. Univariate and bivariate statistical analyses indicated that the variable “animal slaughter” was the only risk factor presenting statistical significance associated with the diagnosis of M. bovis (p < 0.05), demonstrating that macroscopic lesions suspected as being caused by bovine tuberculosis from animals with an in vivo diagnosis were 2.82 - fold more likely to result in a positive M. bovis diagnosis by molecular tests.
Highlights
IntroductionBovine tuberculosis (bTB) is a low prevalence disease. when diagnosed, it causes economic losses by reducing sanitary status and credibility of the herds, as well as consequent meat and milk production losses (Azami & Zinsstag, 2018).The etiologic agent of bovine tuberculosis is Mycobacterium bovis (M. bovis), a bacterium belonging to the Mycobacterium tuberculosis Complex (CMT), distributed worlwide and affecting cattle and several mammal species, including humans
Bovine tuberculosis is a low prevalence disease
The etiologic agent of bovine tuberculosis is Mycobacterium bovis (M. bovis), a bacterium belonging to the Mycobacterium tuberculosis Complex (CMT), distributed worlwide and affecting cattle and several mammal species, including humans
Summary
Bovine tuberculosis (bTB) is a low prevalence disease. when diagnosed, it causes economic losses by reducing sanitary status and credibility of the herds, as well as consequent meat and milk production losses (Azami & Zinsstag, 2018).The etiologic agent of bovine tuberculosis is Mycobacterium bovis (M. bovis), a bacterium belonging to the Mycobacterium tuberculosis Complex (CMT), distributed worlwide and affecting cattle and several mammal species, including humans. Bovine tuberculosis (bTB) is a low prevalence disease When diagnosed, it causes economic losses by reducing sanitary status and credibility of the herds, as well as consequent meat and milk production losses (Azami & Zinsstag, 2018). Humans acquire the infection through contact with aerosols expelled by infected animals or mainly, through the consumption of milk and dairy products not pasteurized or not heat treated from contaminated animals. It is, a serious public health problem, considered a cosmopolitan and re-emerging zoonosis (Medeiros, Marassi, Figueiredo, & Lilenbaum, 2010; Zarden, Marassi, Carvalho, Figueiredo, & Lilenbaum, 2013; Carvalho et al, 2016). In the state of Mato Grosso, Brazil, the Joint Ordinance Sedraf - INDEA/MT 009 of November 14, 2014, established mandatory collection of granulomatous lesions displaying bTB characteristics from cattle slaughtered in slaughterhouses, followed by their shipment to a laboratory indicated by the health authority and notification of the injuries to the Agricultural Defense Service (Portaria Conjunta SEDRAF-INDEA/MT n. 009, 2014)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
