Risk factors and treatment strategies of hypertensive intracerebral hemorrhage and rebleeding

Abstract

Objective To explore the risk factors and treatment strategies of rebleeding in hypertensive intracerebral hemorrhage. Methods Three hundred and twenty patients with hypertensive intracerebral hemorrhage who underwent surgical treatment, admitted to Department of Neurosurgery of General Hospital of Ji’nan Military Area from February 2010 to December 2017, were selected as clinical research cases. Their clinical data were retrospectively analyzed to explore the risk factors of hypertensive intracerebral hemorrhage. Results The incidence of recurrent hemorrhage in hypertensive intracerebral hemorrhage was 11.25% (36 cases). The original hemorrhage site and other hemorrhage sites were detected by CT, and the mortality rate was 61.11%. Rehemorrhage in patients with hypertensive intracerebral hemorrhage was correlated with bleeding volume, blood pressure control, patient agitation, long-term anticoagulant use, coagulation mechanism, INR value and timing of operation (P 0.05). Logistic regression equation was used to analyze the statistical significance of single factor analysis. It was concluded that bleeding volume (>60 mL), systolic blood pressure (≤140 mmHg), long-term oral anticoagulant, abnormal coagulation mechanism, INR value (≥1.4) and time from onset to operation (≤2.5 h) were independent risk factors for recurrent hemorrhage after hypertensive intracerebral hemorrhage (P<0.05). Conclusion Rehaemorrhage of hypertensive intracerebral hemorrhage is significantly correlated with the amount of bleeding, blood pressure control, agitation, coagulation function, long-term oral anticoagulant, INR value, timing of operation and other factors. Appropriate clinical treatment of appeal factors can reduce the rebleeding rate of cerebral hemorrhage. Key words: Hypertensive cerebral hemorrhage; Rebleeding; Risk factors