Abstract

ALTHOUGH certain similarities between folic acid and vitamin B12 as agents involved in haemopoiesis, nucleic acid synthesis and single-carbon transfers are well known, there is very little information on the manner in which these two chemically dissimilar vitamins affect each other. We wish to make a preliminary report of observations which show that the administration of vitamin B12 causes a rise in the serum folic acid - level in patients with nutritional macrocytic anaemia.

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