Abstract
The ultrasound and angiographic parameters of the right chambers of the heart were analyzed in children with pulmonary arterial hypertension (PAH) associated with congenital heart defects. The investigation was conducted in relation to the functional class (degree) of PAH. Right cardiac remodeling was found to depend to a greater extent on afterload (pulmonary artery systolic pressure and pulmonary vascular resistance); moreover, diastolic dysfunction developed just in moderate (Functional Class II) PAH. It was ascertained that there was a prompter development of PAH with myocardial systolic and diastolic dysfunction in the presence of congenital malformations with arterial hypoxemia.
Highlights
The ultrasound and angiographic parameters of the right chambers of the heart were analyzed in children with pulmonary arterial hypertension (PAH) associated with congenital heart defects
The investigation was conducted in relation to the functional class of PAH
Right cardiac remodeling was found to depend to a greater extent on afterload; diastolic dysfunction developed just in moderate (Functional Class II) PAH
Summary
Проведен анализ ультразвуковых и ангиографических показателей правых отделов сердца у детей с легочной артериальной гипертензией, ассоциированной с врожденными пороками сердца. Right cardiac remodeling was found to depend to a greater extent on afterload (pulmonary artery systolic pressure and pulmonary vascular resistance); diastolic dysfunction developed just in moderate (Functional Class II) PAH. It was ascertained that there was a prompter development of PAH with myocardial systolic and diastolic dysfunction in the presence of congenital malformations with arterial hypoxemia. Впедиатрической практике большинство случаев легочной артериальной гипертензии ассоциировано с врожденными пороками сердца (в англоязычной литературе – PAH-CHD) [1,2,3,4,5]. И клиникой сердечно-сосудистой хирургии того же учреждения, гл. Врач Федерального центра сердечно-сосудистой хирургии 660022 Красноярск, ул. Кафедры сердечно-сосудистой хирургии того же учреждения, рук. Научно-методического отдела Федерального центра сердечно-сосудистой хирургии Столяров Дмитрий Павлович – к.м.н., зав. РОССИЙСКИЙ ВЕСТНИК ПЕРИНАТОЛОГИИ И ПЕДИАТРИИ, 3, 2016 ROSSIYSKIY VESTNIK PERINATOLOGII I PEDIATRII, 3, 2016
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