Rieder cells in the cerebrospinal fluid from a patient with viral meningo-encephalomyelitis. A case report.

Abstract

To the best of our knowledge, the presence of Rieder cells, as a possible expression of a cytopathogenic effect of virus infection in vivo, has not been reported previously. Rieder cells are radially segmented mononuclear cells and were demonstrated in the cerebrospinal fluid (CSF) from a patient with a documented Coxsackie B virus meningo-encephalomyelitis. The Rieder cells were classified enzymatically as promonocytes. DNA-analysis of CSF showed some mitotic activity which, however, might be due to stimulated lymphocytes.