Abstract

<i>Rickettsia felis</i>Infections and Comorbid Conditions, Laos, 2003–2011

Highlights

  • Titers against typhus group rickettsiae, spotted fever group rickettsiae, and R. felis were negative in admission and convalescent-phase samples (6day interval) (Table)

  • P. falciparum malaria and dengue were diagnosed, both confirmed by PCR (Table)

  • The fever resolved after treatment with antimalarial drugs and ceftriaxone; neither would be expected to be efficacious for R. felis infection

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Summary

Introduction

Titers against typhus group rickettsiae, spotted fever group rickettsiae, and R. felis (isolate B377 in XTC-2 cells, Australian Rickettsial Reference Laboratory) were negative in admission and convalescent-phase samples (6day interval) (Table). P. falciparum malaria and dengue were diagnosed, both confirmed by PCR (Table). These data suggest that R. felis occurs in Laos, and is possibly emerging, but whether it results in clinical disease or commonly causes subclinical infection is unknown. Among febrile hospitalized patients in Vientiane, 1 case of R. felis infection was serologically diagnosed by using speciesspecific cross-absorption [1].

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