Abstract

Rickettsia felis infection in man, France.

Highlights

  • To the Editor: In August 2008, a 64-year-old man was admitted to the Salon-de-Provence Hospital, France

  • This work was overlooked until 1990, when an ELB agent was found in C. felis fleas by electron microscopy [3]; the agent was demonstrated to be a Rickettsia-like organism

  • R. felis is distributed worldwide, it has not been found in the northern, coldest regions

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Summary

Introduction

To the Editor: In August 2008, a 64-year-old man was admitted to the Salon-de-Provence Hospital, France. Serum testing at the Unité des Rickettsies (Marseilles, France), using a multiple-antigen immunofluorescent assay [1], showed the following titers: spotted fever group (SFG) (e.g., Rickettsia felis, R. conorii, R. aeschlimannii, R. massiliae) 1,024 and 512 for immunoglobulin (Ig) G and IgM, respectively, and typhus group 512 and 256 for IgG and IgM, respectively. Serum was tested by real-time PCR by using a probe that enabled screening for spotted fever and a probe specific for R. felis; results were negative. A Western blot with cross-adsorption [2] showed R. felis as the causative agent (Figure).

Results
Conclusion
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