Abstract
The German Working Group on Indoor Guidelines of the Federal Environment Agency and the States´ Health Authorities is issuing indoor air guide values to protect public health. For health evaluation of phenol in indoor air a qualified working-place study emphasizing the POD hemo- and hepatotoxicity as well as results of a limited inhalation-study which underline neurological effects on rats were used. The Working Group assessed a lowest observed adverse effect level of 21 mg Phenol/m3 in the working-place study and 100 mg Phenol/m3 in the animal-based study. Both toxicological derivatives come to the same result but the working-place study was preferred. By applying a factor of 10 for interindividual variability, a factor of 4.2 for the different exposing-time of workers and usual population and a modifying factor of 2 regarding children a health hazard guide value (RW II) of 0.2 mg phenol/m3 is obtained. A health precaution guide value of 0.02 mg phenol/m3 is recommended.
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