Abstract
Ribosidation of Pyrrolo[2,3‐d]pyrimidines in the Presence of Strong BasesGlycosidation of the pyrrolo[2,3‐d]pyrimidine derivative 3c with the tribenzylated halogenose 6b in strong alkaline medium under the conditions of phase transfer catalysis yields the anomers 9a and 10a. The latter are intermediates in the synthesis of the nucleoside Q as well as for preparation of 7‐methyl‐7‐deazanucleosides. By condensation of the 4‐chloro derivative 3a with the tribenzoylated halogenose 4b and sodium hydride, substitution at the carbon of the acyloxonium ion takes place and a reaction product with orthoamide structure is formed.
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