Synthesis of N—Aroyl—N′—hydroxyethyl (Hydroxyphenyl) Thiourea Derivatives Under the Condition of Phase Transfer Catalysis

Abstract

Reaction of aminoethanol or aminophenol with aroyl chloride and ammonium thiocyanate under the condition of solid-liquid phase transfer catalysis using polyethylene glycol—600 (PEG—600) as the catalyst yielded N—aroyl—N′—hydroxyethyl (hydroxy phenyl) thiourea derivatives. The products have been characterised on the basis of analytical and spectral (IR and ′H—NMR) data.