Abstract
A 7-year-old girl presented with swallowing and respiratory difficulty necessitating artificial ventilation. Her cranial magnetic resonance imaging revealed T2 hyperintensity in the brainstem and cerebrospinal fluid polymerase chain reaction was positive for Coxsackie B4 virus infection. She improved spontaneously by one month. Six months later, she was readmitted with features of primary hypothyroidism and neuromyelitis optica. She improved following corticosteroid and levothyroxine treatment. After 8 months, she had another attack of neuromyelitis optica following withdrawal of prednisolone. Cranial magnetic resonance imaging, cerebrospinal fluid oligoclonal band and vasculitis profile were negative during this attack. She improved following a course of methyl prednisolone. This association of neuroendocrinal manifestations may be due to immunological alterations triggered by Coxsackie B4 virus infection.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.