RHEUMATIC MANIFESTATIONS IN HIV PATIENTS IN TERTIARY HOSPITAL

Abstract

Background: HIV infection is a common disease in India. Rheumatological manifestations ( RM) are very common in HIV infected patients. Rheumatological manifestations are signicant cause of morbidity in these patients. Aim & Objective: To study the clinical spectrum of rheumatic diseases in HIV positive patients and correlate the above with CD4+ counts. Method & Materials: This study was a cross-sectional study carried out in Motilal Nehru Medical College and associated hospitals, Prayagraj. This study was carried out on 104 patients with HIV. After obtaining informed consent, demographic characteristics and details of the diagnosis of HIV will be ascertained. Patients with self-reported history of previous diagnosis of HIV and those on treatment with anti-retroviral agents will be consider to have HIV would need to have further testing of HIV. After this the patients will go through needed investigations to fulll aims and objective of the study. Statistical analysis and interpretation of the data was done by using SPSS Software version 23. Result: This study was carried out on 104 patients with HIV. The mean (SD) of age (Years) of participant in my study was 38.95 (8.93). The maximum number of participants was in age group of 31 -40 years that were 36.5% of total case. The 54.8% of the participants were Male and 45.2% were Female. Patients with rheumatic manifestation, 6 (5.8%) of the participants had Arthritis/Arthralgia and 1 (1.0%) of the participants had Septic Arthritis and 1 (1.0%) of the participants had Osteomyelitis and 1 (1.0%) of the participants had Avascular Necrosis. 0 (0.0%) of the participants had Systemic Lupus Erythematosus and 2 (1.9%) of the participants had Rheumatoid Arthritis and 0 (0.0%) of the participants had Psoriatic Arthritis. Conclusion: The clinical spectrum of rheumatic disease in HIV patients was that, Arthritis/Arthralgia was most common rheumatic manifestation followed by Septic Arthritis and Osteomyelitis. Study showed that with increase in duration of ART regimen the incidence of rheumatic manifestation was decreases.