Abstract
Chromosomal analysis was performed on the tumor tissue in a case of ocular rhabdomyosarcoma. Cytogenetic analysis revealed multiple clonal abnormalities. Derivative(5)t(1;5)(q21;q35) and t(2;11) (q21;q23) were present in all the metaphases analyzed (100%). Translocation(1;19)(q21;q13) was observed in 61% of the metaphases. Other clonal abnormalities present included + i(6p) (85%), i(17q) (38%), 18q + (57%), 4p + (38%), loss of the Y chromosome (33%), and presence of double minutes (12.8%).
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