Abstract
Regulatory T cells (Tregs) were originally identified as immune cells critical for the maintenance of self-tolerance and prevention of autoimmune disease. However, since their discovery in 1995, Tregs have been found to have an expanded role as master-regulatory cells with simultaneous multi-directional functions in immune tolerance involving both innate and adaptive immunity [1]. Similarly, approaches to predict outcomes after lung transplantation through the translation of emerging knowledge of complex immune network continues to evolve.
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