Abstract
Sebaceous adenomas are rare adnexal tumors that are associated with Muir-Torre syndrome. Although sebaceous adenomas are considered benign entities, this is controversial. It has been suggested that sebaceous adenomas are actually low-grade sebaceous carcinomas. In this report, we defend the view that sebaceous adenomas are in fact low-grade sebaceous carcinomas by presenting a lesion with a clinical presentation typical for sebaceous carcinoma with histopathology characteristic of sebaceous adenoma.
Highlights
Sebaceous adenomas are benign, multilobar tumors with sebaceous differentiation [1,2]
Sebaceous carcinomas are potentially fatal malignant adenocarcinomas that most commonly are located on the head and neck as well [17]
Extraocular sebaceous carcinomas range in size from 6 mm to 8 cm [20]
Summary
Multilobar tumors with sebaceous differentiation [1,2]. Sebaceous adenomas are the most common sebaceous tumors associated with Muir-Torre syndrome (MTS) [7], occurring in 68% of MTS patients [2]. This microsatellite instability predisposes MTS patients to sebaceous tumors and internal malignancies, including colorectal and genitourinary neoplasms [8]. The sebaceous tumors occur most frequently on the trunk and may be the first clinical sign of MTS [9,10].
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