Abstract
The aim of the study to estimate the antioxidant action and protecting effect of ethanolic cinnamon extract against CCl4 induced toxicity in male rats. To determine the effect of different concentrations of ethanolic cinnamon extract on male rats that fed a high cholesterol diet that induced hyperlipidemia. The experiment has been conducted in the present study., aimed to evaluate the hepatoprotective, role of Cinnamomum zeylanicum ethanolic extract in carbon tetrachloride (CCl4) induced hepatotoxic male rats, The cinnamon and its oil reported to have many beneficial uses in food preservation due to antioxidant of cinnamon. The Phenolic compounds extracted from cinnamon such as hydroxyl cinnamaldehyde and the hydroxycinnamic acid act as scavengers of peroxide radicals and avoid oxidative damage (Mathew and Abraham, 2006; Leela, 2008). Ranjbar et al, (2006) observed individuals consuming cinnamon tea showed increased total serum antioxidant status, increased thiols such as glutathione, NADPH, NADH, SOD, and decreased lipid peroxidation.
Highlights
Antioxidant means "against oxidation", antioxidants work to guard lipids, proteins and nucleic acids from peroxidation by radicals
Antioxidants are effective because they are ready to give up their possess electrons to free radicals
The soluble polymeric compounds extraced from cinnamon have insulin enhancing biological activity in the in vitro assay measuring the insulin dependent effects on glucose metabolism and function as antioxidants, these results suggest that compounds present in cinnamon may have useful for treatment of diabetes (Anderson et al, 2004)
Summary
Antioxidant means "against oxidation", antioxidants work to guard lipids, proteins and nucleic acids from peroxidation by radicals. They hinder or interval the oxidation of other particles by stopping the initiation or spread of oxidizing chain reactions. Medical plants are the oldest friends of humanity They provided food and shelter and served the mankind to cure different aliments, and according to the world health organization (WHO) traditional systems of medicines always played important role in the global health. The antioxidants comprise many materials that have important in guarding biological systems to avoid the toxic effects of oxidative stress on carbohydrates, lipids, proteins and DNA Figure (21), (Yuji et al, 2010)
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