Abstract
Chirality has an important impact in chemical and biological research, since most active substances possess chirality. Usually, the performance and properties of chiral enantiomers exhibit significant differences in terms of biochemical activity, toxicity, transport mechanism and pathways of metabolism. Thus, developing effective method to achieve chiral recognition is of great significance and has always been a hot topic in chemo/biological study. In recent years, the electrochemical technologies, which can offer many advantages over the other conventional methods, have received considerable attention in chiral recognition. In this review, a comprehensive and critical detail of the trends on electrochemical chiral recognition in the last 5 years have been presented. In addition, some critical challenges and prospects in the field of electrochemical chiral recognition are also discussed in the latter part.
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