Review: Polymeric-Based 3D Printing for Tissue Engineering.

Geng-Hsi Wu,Shan-Hui Hsu

doi:10.1007/s40846-015-0038-3

Geng-Hsi Wu, Shan-Hui Hsu

Open Access

https://doi.org/10.1007/s40846-015-0038-3

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Abstract

Three-dimensional (3D) printing, also referred to as additive manufacturing, is a technology that allows for customized fabrication through computer-aided design. 3D printing has many advantages in the fabrication of tissue engineering scaffolds, including fast fabrication, high precision, and customized production. Suitable scaffolds can be designed and custom-made based on medical images such as those obtained from computed tomography. Many 3D printing methods have been employed for tissue engineering. There are advantages and limitations for each method. Future areas of interest and progress are the development of new 3D printing platforms, scaffold design software, and materials for tissue engineering applications.

Highlights

Three-dimensional (3D) printing, referred to as additive manufacturing, is a technology that allows for customized fabrication through computer-aided design. 3D printing has many advantages in the fabrication of tissue engineering scaffolds, including fast fabrication, high precision, and customized production
Future areas of interest and progress are the development of new 3D printing platforms, scaffold design software, and materials for tissue engineering applications
Three-dimensional (3D) printing is a commonly used term that is often considered synonymous with additive manufacturing. 3D printing has drawn a lot of public attention, especially for its use in medical research

Summary

Introduction

Three-dimensional (3D) printing is a commonly used term that is often considered synonymous with additive manufacturing. 3D printing has drawn a lot of public attention, especially for its use in medical research. With tissue and organ regeneration, the hurdles of traditional therapeutic methods may be overcome by autologous transplantation. As these technologies gain acceptance, the shortage of donor organs or chronic rejection of transplants may no longer be a problem. Scaffolds play an important role in tissue engineering. Conventional scaffold fabrication techniques have been improved, the physical properties of scaffolds fabricated by these methods still have limitations (i.e., controlling scaffold pore size, geometry, and porosity). Unlike conventional scaffold fabrication techniques, which are highly process-dependent, additive manufacturing is design-dependent for scaffold fabrication. By adjusting the parameters of manufacturing, tissue engineering scaffolds can be made to fit different purposes

Fused Deposition Modeling

Liquid Frozen Deposition Manufacturing

Digital Light Processing

Selective Laser Sintering

Other Techniques

Challenges and Prospects