Abstract
Peptic Ulcer Disease (PUD) is one of the major problems of the gastrointestinal tract occurs in the stomach, duodenum and oesophagus. PUD is characterized by mucosal damage either by pepsin, gastric acid secretion or bacterial infection. Apart from infection due to gram negative bacteria-Helicobacter pylori, regular consumptions of the medications like, NSAIDS, steroids and excessive stress are also some major causes of the PUD. Complications of PUD may include bleeding, perforation, and blockage of the stomach. The PUD is an emerging health challenge in the developed and developing countries. Commonly use of potent synthetic antiulcer chemotherapy arises with adverse effects that might be a cause of serious health challenge. Traditional utilization and scientific reports of medicinal plants in the management of peptic ulcer-like-symptoms urge to redesign the existing clinical approach of using synthetic drugs for the treatment of PUD and adopt the scientifically proven plant drugs for the treatment of PUD which might free or have lesser adverse effects as compared to the synthetic chemotherapy. The review might bestow a strategic planning for the treatment of PUC to the medical practitioners and a newer scope to the researchers to explore the traditional claims of the plant drugs.
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