Abstract
Systems for orodispersible drug delivery are widely used to increase patient compliance and bioavailability. Because of their enhanced solubility, stability profiles, and higher patient compliance compared to traditional tablets and capsules, orodispersible tablets (ODTs) have drawn a lot of attention in the last thirty years. The review of possible developments in ODT technology for drug delivery applications is the article's main goal. ODTs are prepared using a variety of methods, such as mass extrusion, tablet moulding, sublimation, freeze drying, and direct compression. ODTs may be the better option, particularly for GI-sensitive medications and for patients who fall into the paediatric, geriatric, bedridden, postoperative, or other categories and may have trouble swallowing traditional tablets and capsules. When placed on the tongue, ODTs-solid dosage forms containing medication-disintegrate quickly, often within a few seconds. ODTs have higher acceptability because of their increased bioavailability and stability, as well as patient compliance. This article examines current developments in ODT development, including new technologies, drug candidate suitability, and ODT characterization.
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