Review on Anti-tumor activity, Immunomodulatory and neuromodulatory properties of Piper longum Linn

Abstract

In ancient times, people were very keen on using natural plant products as a potential drug for its hepatoprotective, respiratory protective neuroprotective, and cardio-protective activities. However, in today’s advanced world of medicine use of ayurvedic medicine is replaced by allopathic medicine and antibiotic-resistant bacteria, untreatable viruses, and other great concerns have been aroused. Now there is an emerging need for alternatives that are typically safe, natural, and cost-effective. In this context, this review aimed to offer essential data focusing on the traditional use, phytochemistry, and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant. In the current review, we discussed the medicinal effects of Piper longum on the different sections of the human body. The finding showed that it is rich in many phytochemicals mainly piperine and piperlongumine. And this particular herb’s therapeutic potential can be utilized as the primary medicine for curing diseases related to the respiratory, immune, digestive, and cardiovascular systems. Additionally, the therapeutic potential of this herb can be utilized to suppress the growth of cancerous cells. In most of the studies conducted in different in-vitro and in-vivo models, the above-mentioned herb was found nontoxic and suited for the treatment of various diseases. Further, due to its low economical cost and easy availability, it is considered a suitable medicinal herb. Moreover, plant-based therapy can be used as an excellent.