Review: immunomodulatory effects induced by phenolic compounds

Abstract

Recently, the population has turned its attention to a healthier diet, with a diet richer in fruits, vegetables and vegetables. The search for a healthy diet is derived from the nutraceutical capacity of natural foods, and the beneficial effects of these, are attributed, at least in part, to the presence of phenolic compounds. Phenolic compounds are secondary metabolites present in plants, biologically active and have aromatic rings and hydroxyl groups in their structure. The objective of this work was to carry out a survey on the interaction capacity of phenolic compounds with the immune system, as well as to evaluate the current status of this topic in the academic community. The keywords “phenolic compounds” and “immunomodulatory activity” were used on three research platforms (Scielo, PubMed and Periódicos CAPES). The results showed that there is a growing interest in the academic community in the topic addressed, which is justified by the ability of these compounds to interact with various immunological responses, such as inflammatory activity and oxidative balance, proliferation and action of white cells, among others.