Reversible splenial lesion of the corpus callosum secondary to severe intracranial hypertension in children: a case report

Abstract

Introduction. Reversible lesions in the splenium of the corpus callosum are a recognized radio-clinical entity, which is rarely associated with idiopathic intracranial hypertension, especially in children. We present a case. Case report. We describe the case of an 11-year-old prepubescent female patient with no significant medical history. She presented with idiopathic intracranial hypertension syndrome and exhibited a nodular lesion in the splenium of the corpus callosum on the MRI scan. Initial medical treatment with acetazolamide and a subtractive lumbar puncture failed to improve the patient's condition. Consequently, an emergency ventriculoperitoneal shunt procedure was performed, resulting in a favorable clinical outcome. A follow-up MRI was conducted six months later, revealing normalization of the imaging results. Conclusion. Further studies are needed to understand the pathophysiology of reversible lesions in the splenium of the corpus callosum during idiopathic intracranial hypertension.