Reverse remodeling of left ventricular evaluated by real-time three-dimensional echocardiography in patients with coronary artery bypass graft

Abstract

Objective To evaluate the clinical application value of reverse remodeling of left ventricular function and synchronism on coronary artery disease（ CAD）patients after coronary artery by-pass graft（CABG）using real-time three-dimensional echocardiography（RT-3DE）. Methods Left ventricular end-diastolic volume（ LVEDV）,16-segments synchronized indices,peak ejection rate（ PER）, peak early filling rate（PFR）were measured by RT-3DE in 31 patients with three-vessels of CAD preop-eration and post-operation 1 month after CABG. Thirty normal people as control group without coronary stenosis,which were verified by coronary angiography. Results There was significant difference between patients group and control group,LVEDV,Tmsv16-SD and Tmsv16-Dif were significantly increased（ P﹤0. 01）in patients group,left ventricular ejection fraction（ LVEF）,PER and PFR were significantly decreased（P﹤0. 01）in patients group. There was significant difference between pre-operation and post-operation 1 month,LVEDV,Tmsv16-SD and Tmsv16-Dif were significantly decreased in post-operation group,LVEF,PER and PFR were significantly increased（ P﹤0. 01 ）in post-operation group. Conclusions Left ventricular remodeling is induced by three-vessels lesion in patients with CAD. CABG can reverse left ventricular remodeling. The left ventricular reverse remodeling can be evaluated by RT3DE in CAD after CABG. Key words: Real-time three-dimensional echocardiography; Coronary artery bypass graft; Re-verse remodeling; Synchrony