RETROSPECTIVE ASSESSMENT OF THE COVID-19 INCIDENCE AND VACCINATION OF THE STAFF MEMBERS OF THE NAMS OF UKRAINE RESEARCH INSTITUTIONS

Abstract

Introduction. In the conditions of the COVID-19 pandemic, there is an obvious need to achieve the appropriate level of collective immunity of personnel in medical institutions to ensure the possibility of full functioning and providing medical assistance to patients. Aim: to analyze information about the incidence of COVID-19 and SARS-CoV-2 vaccination of the staff of the Research Institutions of the National Academy of Sciences of Ukraine. Material and methods. Depersonalized information on COVID-19 disease and vaccination and levels of SARS-CoV-2 antibodies among the staff of the Research Institutions of the National Academy of Sciences of Ukraine as of November 22, 2021, statistical methods. Results. In the Research Institutions of the National Academy of Medical Sciences, the appropriate level of collective immunity was formed among the staff due to vaccinated persons and convalescents. At the pre-morbid stage, the levels of anti-SARS-CoV-2 antibodies of the IgG class were low in most of the examinees, after the disease they increased, however, in 8.5% - 10.3% of workers recovery after the disease was not accompanied by an increase in the level of anti-SARS-CoV-2 antibodies, which may carry the risk of recurrent disease. Almost a third of the examined had protective levels (>4.0) of anti-SARS-CoV-2 antibodies even before the start of vaccination, having neither a documented fact nor an anamnestic data on the disease of COVID-19, which may indicate the transferred asymptomatic forms of the infection or the course of it have been under the guise of a banal acute respiratory viral disease. Adverse reactions to vaccination were mostly mild, in the form of fever, pain in the area of vaccine injection, muscle pain, rarely - dizziness, ranging from 10.2% to 33.15% depending on the type of vaccine. Conclusion. Given the continuation of the pandemic and conflicting data on the duration of immunity after vaccination or the transferred disease, it is advisable to continue monitoring the incidence of COVID 19 and assessing the levels of anti-SARS-CoV-2 antibodies in order to maintain collective immunity in each Research Institution of the National Academy of Medical Sciences of Ukraine. Key words: SARS-CoV-2, COVID-19, morbidity, vaccination