Abstract
ObjectivesTo investigate the clinical and pathological features of metanephric adenoma (MA) and the clinical outcome after retroperitoneal laparoscopic nephron-sparing surgery.MethodsSix out of 183 partial nephrectomies performed during January 2009 to August 2014 were confirmed to be MA confirmed by postoperative pathological study. Perioperative parameters of the six patients were then retrospectively collected, analyzed and compared with current literature, including warm ischemia time (WIT), total operation time, estimated blood loss (EBL), positive surgical margin (PSM), and complications. Surgical and oncological outcome of all six patients were evaluated based on a mean follow up of 17 months (5–48 months).ResultsTumors in all six cases were all successfully removed by partial nephrectomy. Mean WIT was 24.7 min (19–35 min). Mean operation time was 103.6 min (82–147 min). Mean EBL was 53.5 ml (20–85 ml). No conversion, transfusion or other major complication were observed in all six cases. Postoperative pathology confirmed negative surgical margin in all six cases. During a mean of 17 month follow up (5–48 months), no local recurrence or metastasis were found in all six cases.ConclusionMA is a rare benign primary kidney epithelial cancer, which could hardly be differentiated from renal malignancies based on preoperative imaging. Our data suggested that retroperitoneal laparoscopic partial nephrectomy can be used for surgical treatment of MA, in terms of tumor control and preservation of renal function.
Highlights
Metanephric adenoma (MA) is a very rare benign tumor derived from kidney epithelial tissue, with less than 100 cases reported in current literature (Kuroda et al 2003)
The purpose of this paper is to describe our preoperative imaging and postoperative histological diagnosis of MA in six patients, as well the surgical technique and oncological outcome based on a mean follow up of 17 months (5–48 months)
Perioperative parameters All tumors were successfully removed by retroperitoneal laparoscopic partial nephrectomy (RLPN) without conversion or transfusion
Summary
Metanephric adenoma (MA) is a very rare benign tumor derived from kidney epithelial tissue, with less than 100 cases reported in current literature (Kuroda et al 2003). The clinical symptoms and signs of MA are very similar to those of malignant renal tumors, which make the differential diagnosis and subsequent surgery planning a difficult task. Surgery planning for MA is still identical to renal cell carcinoma, while the nature of the tumor can only be confirmed by postoperative pathological study (Kuroda et al 2003). We reported 6 cases of MA confirm by postoperative pathological study. The purpose of this paper is to describe our preoperative imaging and postoperative histological diagnosis of MA in six patients, as well the surgical technique and oncological outcome based on a mean follow up of 17 months (5–48 months)
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