Abstract

Objectives To evaluate the perioperative condition and clinical effect in retroperitoneal laparoscopic partial nephrectomy(RLPN) for early-stage renal carcinoma.Methods The clinical date of 36 patients who underwent retroperitoneal laparoscopic partial nephrectomy were retrospectively compared with those of 38 patients who underwent open partial nephrectomy (OPN) for early-stage renal carcinoma,including mean operation time,warm ischemia time,mean estimated blood loss,postoperative drainage volume,blood transfusion rate,resumption of oral intake,postoperative hospital stay and complications incidence from January 2008 to December 2012.Results There were no significant difference in sex,age,tumor size and preoperative renal function in two groups.The mean operation time of two groups was (142.67 ±41.26) mins and(128.33 ± 32.27) mins,the warm ischemia time was (29.68 ± 4.92) mins and (24.85 ± 3.66) mins.RLPN group showed a bit longer than OPN group.The mean estimated blood loss of two groups was (138.25 ± 48.13) ml and (236.67 ±82.37)ml,the postoperative drainage volume was (88.96 ±25.37)ml and (126.56 ±33.29)ml,the resumption of oral intake was (2.21 ±0.49)d and (3.32 ±0.61)d,the postoperative hospital stay was (7.28 ± 1.47)d and (9.39 ± 1.70)d,RLPN group was superior in these statistical variables to OPN group(P < 0.05).The complications incidence of two groups was 13.9% (5/36) and 13.2% (5/38) and it shows no significant difference(P >0.05).Conclusions RLPN is comparably safe as OPN,and takes obvious advantage in minimally invasive surgery with well clinical effects,and would be a safe and reliable surgery treatment for early-stage renal carcinoma. Key words: Kidney Neoplasms ; Nephrectomy ; Laparoscopy

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