Abstract
It is thought that Malaria parasites live in red blood cells and make them stick to the inside of small blood vessels, particularly this causes the unique whitening of eye blood vessels. The light-sensitive tissue in the eye is also affected because the parasites disrupt the supply of oxygen and nutrients These changes, known as malarial retinopathy, include white, opaque patches, whitening of the infected blood vessels, bleeding into the retina and swelling of the optic nerve. Our study aims to demonstrates malarial retinopathy in patients presented with neurological manifestations of malaria. A cross-sectional Hospital based study included all patients with malaria seen during the period between 1-1-2019 and 25-4-2019. Almost 40 patients with neurological manifestations of malaria were included in the study (29 having cerebral malaria, 3 with post malarial cerebellar ataxia, 2 with post malarial syndrome and abnormal movement, one with peripheral neuropathy, one with proximal myopathy, one had cerebral infaction, one had cerebral haemorrhage, one had sagital sinus thrombosis and one had six nerve palsy). Out of 29 patients with cerebral malaria 14 were children and 15 were adult. Malarial retinopathy changes were detected only among those with cerebral malaria (7 children and 3 Adult). The eye can provide a very reliable way of diagnosing cerebral malaria. By looking at the changes to the retina Our research demonstrates that the detection of malarial retinopathy is a much needed diagnostic tool in cerebral malaria, and can identify those children at most risk of death.
Published Version
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