Retention and elimination of cumyluron by the brackish water bivalve Corbicula japonica

Abstract

We studied the retention and elimination of cumyluron by the brackish water bivalve Corbicula japonica. Although a large concentration of cumyluron was rapidly eliminated from the bivalve within the first few days of the depuration phase, the elimination rate decreased and radioactivity (approximately 0.01 ppm) was detected in all tissues of the bivalve even on Day 42 of the depuration phase; however, no tissue-specific retention was observed. Cumyluron was mostly eliminated in an unchanged form, probably because of weak phase I metabolic activity. This may be one of the causes of the long-term retention of cumyluron at a low level in this bivalve.