Abstract
Anaplastic glioma is one of the most dangerous and serious brain tumors. Modern microsurgery, radiation, chemotherapy, and other all-encompassing therapeutic techniques can lead to inadequate clinical treatment results for gliomas. High dose re-irradiation with concurrent chemotherapy is a workable treatment option for patients with metastases and recurrent anaplastic gliomas, even when significant treatment volumes are being employed to target non-enhancing tumor components. The issue of glioma metastasis is likewise unsettled and poorly understood. Single serial observations of high-grade glioma metastases are reported in the international literature, with glioblastoma accounting for the majority of these cases. Isolated cases of anaplastic glioma metastasis have been recorded in the majorit y of observations.
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