Abstract
We have introduced two endoscopic treatments for early gastric cancer: endoscopic mucosal resection using a cap-fitted panendoscope (EMRC), and endoscopic laser therapy using a Nd-YAG laser. Thirty-two patients (34 lesions) with gastric cancer were treated by Nd-YAG laser; including 23 initial-therapy cases (25 lesions) and 9 second-therapy cases representing failures of endoscopic mucosal resection or endoscopic ethanol injection. Endoscopic laser therapy was performed safely without complication in all patients. Three patients had residual cancer, and 2 of these required surgery. Six patients died from other disease. Endoscopic laser therapy can remove early gastric cancer even when the lesion has ulceration or submucosal invasion, and has a powerful hemostatic effect. It is a safe and effective treatment for early gastric cancer.
Highlights
Neodymium yttrium aluminum garnet (Nd-YAG) laser treatment has been used to alleviate obstruction from unresectable malignant lesions of the gastrointestinal tract [1], to arrest hemorrhage from gastric vascular ectasia [2], and to treat early gastric cancer curatively [3].Curative endoscopic treatment for early gastric cancer has become accepted at many institutions in Japan, incorporating such specific modalities as polypectomy, mucosal resection (EMR), laser, heatprobe, microwave, injections and hyperthermia
We examined our results with endoscopic laser therapy and evaluated its role in the endoscopic treatment of early gastric cancer
Twenty-four in 32 patients were treated on an ambulatory basis with endoscopic laser therapy
Summary
Neodymium yttrium aluminum garnet (Nd-YAG) laser treatment has been used to alleviate obstruction from unresectable malignant lesions of the gastrointestinal tract [1], to arrest hemorrhage from gastric vascular ectasia [2], and to treat early gastric cancer curatively [3]. Curative endoscopic treatment for early gastric cancer has become accepted at many institutions in Japan, incorporating such specific modalities as polypectomy, mucosal resection (EMR), laser, heatprobe, microwave, injections and hyperthermia. We have introduced two endoscopic treatments for early gastric cancer. The second is a laser therapy using a medical Nd-YAG laser system (MC2100) [7]. We examined our results with endoscopic laser therapy and evaluated its role in the endoscopic treatment of early gastric cancer
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