Abstract
Treatment and investigation results of 128 IIA - IIIB stage cervical cancer patients treated by concurrent chemoradiother-apy with combined intracavitary and interstitial brachytherapy were analyzed. Interstitial brachytherapy allowed significantly increase a dose to high risk clinical target volume without elevation of the dose to surrounding organs at risk. Three-year relapse free survival did not differ significantly between intracavitary and interstitial brachytherapy groups. However analysis of local control rates depending on tumor size ant treatment modality showed higher three year relapse free survival rate for tumors > 5 cm treated by interstitial brachytherapy. Therefore interstitial brachytherapy for locally advanced cervical cancer is quite safe and effective treatment modality and could be used in daily clinical practice. But to do final conclusions we need to recruit more patients and longer follow up.
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