Abstract
The present investigation delves into the reparative efficacy of Curcuma longa extract in mitigating the deleterious effects induced by varying concentrations of cypermethrin in Swiss albino mice (Mus musculus). A significant increase was observed at the highest dose of cypermethrin (200 mg/kg of body weight of Swiss albino mice) in biochemical parameters namely Aspartate Aminotransferase (AST), 49 % Alanine Aminotransferase (ALT), 58 % Blood Urea Nitrogen (BUN), 108 % Creatinine 247 %. The discernible outcome is evidenced by a gradual recovery in the damage inflicted by cypermethrin. Significant changes were observed, including an approximate 16% decrement in AST, 7% reduction in ALT, substantial 45% decline in BUN levels, and a pronounced 76.16% decrease in creatinine levels. Further, haematological indices demonstrate a commendable recovery pattern, with a 10% resurgence in neutrophils, 3% restitution in lymphocytes, 6% recuperation in basophils, 2% restoration in monocytes, and 10% revival in eosinophils. These findings substantiate a promising therapeutic role for C. longa extract within the realm of pharmaceutical industries, signifying its potential utility in countering cypermethrin-induced physiological disbalance.
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