Abstract
Response to Commentary by Giuseppe Mancia
Highlights
Med One investigators, such pragmatic clinical trials afford an opportunity to study therapeutic inertia and adherence with medications [7]
He argues that randomized trials are not feasible to certain areas, epidemiology, diagnosis, and patients’ follow-up [2]
All observational studies are subject to confounding; there are numerous examples in the literature of observational studies or expert opinion being contradicted by the results of well-conducted randomized clinical trials [3,4]
Summary
Med One investigators, such pragmatic clinical trials afford an opportunity to study therapeutic inertia and adherence with medications [7]. Mancia on our manuscript [1].
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