Abstract

The paper deals with the problem of detection of radio-protective effects during irradiation. The method used is based on the fact that the known effective pharmacological and chemical radioprotectives (aminoethylthiouronium bromide HBr (AET), cystamine, sodium fluoroacetate (FAc), 5-hydroxytryptamine (5-HT), 5-methoxytryptamine (5-MT) and others) interfere directly or indirectly with enzymatic steps in energy metabolism of the organism. In mammals they induce at the same time an increase of resistance against ionizing radiation and a decrease in the respiratory gas exchange expressed by a depressed oxygen consumption.

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