Abstract

Bilateral section of vagi nerves and denervation of carotid bodies prevented the gasping, ataxic and periodic respirations produced by purified scorpion toxin ( Tityus serrulatus) in the rat. The apnea recorded in intact rats after toxin injection was of long duration in comparison with that observed in denervated animals. Bilateral vagotomy abolished the apnea observed between gasping respirations. It is concluded that the respiratory arrhythmias produced by scorpion toxin in the rat are mainly due to stimulation of peripheral receptors and are, therefore, reflex in nature.

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