Abstract
Robust evidence syntheses, health technology assessments (HTAs) and trustworthy guidelines are the cornerstones of informed healthcare decision making and for moving the best-available research evidence into policy and practice. The Coronavirus disease 2019 (COVID-19) pandemic and subsequent infodemic–the rapid spread and generation of accurate and inaccurate information–represents an unprecedented global challenge. The infodemic has impacted not just public trust in the healthcare system, but also the health sector's ability to rapidly respond to misinformation.
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