Abstract
RESUMO Introduction: In recent years, there was an increased interest on the effects of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on skeletal muscle due to its anti-catabolic effects. Objectives: To investigate the effect of HMB supplementation on body composition, muscular strength and anabolic-catabolic hormones after resistance training. Methods: Twenty amateur male athletes were randomly assigned to supplement and control groups in a double-blind crossover design and participated in four weeks resistance training. Before and after the test period fasting blood samples were obtained to determine anabolic (the growth hormone and testosterone) and catabolic (cortisol) hormones, and fat mass, lean body mass (LBM) and muscular strength were measured. Dependent and independent t-tests were used to analyze data. Results: After the training period, there were no significant differen-ces between the groups with respect to fat mass, LBM and anabolic-catabolic hormones. HMB supplementation resulted in a significantly greater strength gain (p≤0.05). Conclusion: Greater increase in strength for HMB group was not accompanied by body composition and basal circulating anabolic-catabolic hormonal changes. It seems that HMB supplementation may have beneficial effects on neurological adaptations of strength gain.
Highlights
In recent years, there was an increased interest on the effects of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on skeletal muscle due to its anti-catabolic effects
BMI: body mass index, LBM: lean body mass. *Significant difference compared to pre-training values (p≤0.05)
The present study investigated the effect of HMB supplementation on body composition, muscular strength and anabolic-catabolic hormones after four weeks resistance training in amateur athletes
Summary
There was an increased interest on the effects of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on skeletal muscle due to its anti-catabolic effects. Conclusion: Greater increase in strength for HMB group was not accompanied by body composition and basal circulating anabolic-catabolic hormonal changes. It seems that HMB supplementation may have beneficial effects on neurological adaptations of strength gain. Studies examining the effects of HMB supplementation on strength and body composition have demonstrated that HMB supplementation, in combination with a resistance training program, resulted in increased muscular strength and lean body mass (LBM) and tended to decrease fat mass[4,5]. It has been suggested that HMB supplementation with 1.5 to 3 g per day reduces muscle proteolysis and increases strength and muscle mass after 3-8 weeks strength training[6,7] These findings aren’t confirmed by other studies[8,9]
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