Abstract
Researches on the Pharmacological Effects of Eicosapentaenoic Acid
Highlights
In the late 1970s, Dyerberg et al [1] highlighted the cardio protective effect of dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the first time
Fish oils are the most common source of omega-3 polyunsaturated fatty acids (n-3 PUFAs), mainly eicosapentaenoic acid (EPA). It has been pointed out protective effects and beneficial effects of EPA on body weight reduction, heart health, blood lipid profile, cardiovascular diseases and other diseases
Eicosapentaenoic acid (EPA) is typical omega-3 polyunsaturated fatty acids found in fish and fish oils, and it is derived from another n-3 PUFA, α-linolenic acid (α-LNA) (Figure 1) [4,5,6]
Summary
In the late 1970s, Dyerberg et al [1] highlighted the cardio protective effect of dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) for the first time. It has been pointed out protective effects and beneficial effects of EPA on body weight reduction, heart health, blood lipid profile, cardiovascular diseases and other diseases. Given the side effects and limitations of pharmacologic therapies, it is greatly needed to develop nutritional interventions which may prevent or treat obesity and inhibit its associated diseases.
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