Abstract
Tissue expression and blood level of YKL-40 protein are elevated ia patients with tumor.The protein may have a role in cancer cell proliferation,infiltration,metastasis and remodelling of tumor stroma.Elevated YKL-40 levels are highly associated with short survival and poor response to treatment for patients.Thus,YKL-40 may serve as a biomarker in diagnosis of disease,evaluation of severity and assessment of prognosis.It's more likely to be a new target for anti-tumor treatment. Key words: Neoplasms; YKL-40 protein
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